Abstract: Routes of Exposure–Dermal
The skin is the largest organ in the body by area, if not by weight, and is of great interest to toxicologists. In this presentation, we will consider the anatomy of the skin and topics such as metabolism, penetration of drugs, and toxicology and pharmacology, including the relationship between dermal drug application and systemic toxicity. The presentation will have a particular focus on drug delivery and aspects of purpose (not all dermally applied drugs are intended to have an effect
in the skin), formulation/dosage forms, penetration and kinetics. From a toxicological testing viewpoint, we will consider species selection (including selection of both non-rodent and rodent species in programme design strategies), and relevance to humans; study design and study performance will be discussed.
Modules are available for purchase individually or as a discounted set of six modules. Once the live module presentation concludes, registrants will have on-demand access to the modules for 30 days from the time each archive is first accessed. Each module is 90 minutes or fewer in duration.
Webinar registration is intended for single-person use only.